Projects

A01 
Spatio-temporal control of FGF2 recruitment and membrane translocation exerted by phosphoinositide and kinase switches

Prof. Dr. Walter Nickel (BZH Heidelberg)
Prof. Dr. Helge Ewers (FU Berlin)

A02
Acute control of intracellular trafficking through Rab GTPases in living tissues in Drosophila
Prof. Dr. Michael Boutros (Med. Fakultät Mannheim/Heidelberg)
Prof. Dr. P. Robin Hiesinger (FU Berlin)

A03
Ca2+ and lipid control of vesicle fusion in ß-cells and neurons

Prof. Dr. Stephan Sigrist (FU Berlin)
Dr. Alexander M. Walter (FMP Berlin)

A04
Neurotransmitter release: Spatio-temporal characterization of membrane fusion intermediates

Prof. Dr. Thomas Söllner (BZH Heidelberg)
Prof. Dr. Christian Rosenmund (Charité Berlin)

A05
The palmitoylation switch in activated T cells

Prof. Dr. Christian Freund (FU Berlin)
Prof. Dr. Britta Brügger (BZH Heidelberg)

A06
Spatio-temporal control of CD95-activation mode

Prof. Dr. Ana Martin-Villalba (DKFZ Heidelberg)
Prof. Dr. Helge Ewers (FU Berlin)

A08
Phosphoinositide-based switches in endocytic membrane traffic and signaling

Prof. Dr. Volker Haucke (FMP Berlin)

A09
Phosphoinositide-based switches in polarized sorting and signaling

Dr. Steeve Boulant (Med. Fakultät Heidelberg)

A12
Effect of membrane lipid phosphorylation on protein recruitment at molecular and cellular scales

Prof. Dr. Frank Noé (FU Berlin)
Prof. Dr. Cecilia Clementi (FU Berlin)

A14
Molecular switches regulating stress granule oscillation
Dr. Alessia Ruggieri (Med. Fakultät Heidelberg)
Prof. Dr. Georg Stoecklin (Med. Fakultät Mannheim / Heidelberg)

 

A15
Temporal control of spliceosome activity to modulate splicing switches during T cell activation and serum stimulation

Prof. Dr. Florian Heyd (FU Berlin)
Prof. Dr. Markus Wahl (FU Berlin)

A16
Functional characterization of the molecular timer of the circadian clock of Neurospora crassa

Prof. Dr. Michael Brunner (BZH Heidelberg)
Prof. Dr. Hans-Peter Herzel (Charité Berlin)

A17
Chemical control of PER2-CRY1 heterodimerization: impact on circadian oscillations

Prof. Dr. Achim Kramer (Charité Berlin)
Prof. Dr. Hans-Peter Herzel (Charité Berlin)

A18
A SUMO switch in EGF receptor signaling

Prof. Dr. Frauke Melchior (ZMBH Heidelberg)
Prof. Dr. Nils Blüthgen (Charite - Universitätsmedizin Berlin)

A19
STARD3 as a cellular switch determining organelle contact sites

Dr. Doris Höglinger (BZH Heidelberg)

A20
Nanoscale regulation of small GTPase switches at the trans-Golgi network/recycling endosomal interface

Prof. Dr. Francesca Bottanelli (FU Berlin)

A21
Switching antigens by the exchange catalyst HLA-DM

Prof. Dr. Christian Freund (FU Berlin)
Prof. Dr. Thomas Höfer (DKFZ Heidelberg)

A22
Metabolic switches regulating NADPH availability and stress resistance

PD Dr. Tobias Dick (DKFZ Heidelberg)
Prof. Dr. Markus Ralser (Charité – Universitätsmedizin Berlin)

A23
Control of organelle biogenesis by the Lipin switch

Dr. Sebastian Schuck (ZMBH)
Prof. Dr. Oliver Daumke (MDC Berlin)

A24
Molecular switches in the TGF-β signaling pathway – the role of inositol pyrophosphate messengers

Prof. Dr. Dorothea Fiedler (FMP Berlin)
Prof. Dr. Ursula Klingmüller (DKFZ Heidelberg)

Z02
Quantitative Image Processing

Prof. Dr. Helge Ewers (FU Berlin)

Z03
Administration

Prof. Dr. Walter Nickel (BZH Heidelberg)

Z04
Tools to generate and study molecular switches in living cells

Prof. Dr. Kai Johnsson (MPI Heidelberg)
Prof. Dr. Britta Brügger (BZH Heidelberg)